Bio
My program of research focuses on the regulation of mitochondrial function and metabolism during cardiac and skeletal muscle differentiation and remodeling, including disease related conditions such as diabetic cardiomyopathy, insulin resistance, and hypoxia/ischemia,; as well as physiological stimuli such as exercise and contractile activity. Specifically, my laboratory studies the transcriptional regulation and post-translational modification of the Bcl-2 family members Nix and Bnip3 utilizing both primary and immortalized cells, differentiated human induced pluripotent stem cells, and conditional knockout mice.
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Currently accepting students.